Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 4/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512964 | 1.00 | NR1D1 (0.48) | NR1D1NR1H3MAPTMEN1KMT2A | |
| SCHEMBL7673699 | 0.88 | NR1D1 (0.48) | NR1D1NR1H3TSHRCYP11B1CYP11B2 | |
| SCHEMBL24872544 | 0.82 | TRPV4 (0.45) | CYP11B1CYP11B2GPR52 | |
| SCHEMBL30037290 | 0.81 | IDH1 (0.43) | TSHRHPGDKDM4EHSD17B10GPR52 | |
| SCHEMBL3512013 | 0.81 | IDH1 (0.43) | TSHRHPGDKDM4EHSD17B10GPR52 | |
| SCHEMBL3512037 | 0.78 | TAAR1 (0.44) | CYP11B1CYP11B2ALDH1A1HPGDKDM4E | |
| SCHEMBL29442825 | 0.77 | MEN1 (0.47) | MAPTMEN1KMT2APABPC1CYP11B1 | |
| SCHEMBL28701298 | 0.77 | MEN1 (0.47) | MAPTMEN1KMT2APABPC1CYP11B1 | |
| SCHEMBL21384007 | 0.77 | GPR52 (0.43) | CYP11B1CYP11B2GPR52 | |
| SCHEMBL29442797 | 0.77 | GPR52 (0.43) | CYP11B1CYP11B2GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |