Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MC5R | P33032 | 2/20 | 0.48 |
| ▸ | MC1R | Q01726 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996583 | 0.89 | KMT2A (0.51) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3103327 | 0.88 | MC5R (0.55) | MAPTMC5RMC1RMEN1KMT2A | |
| SCHEMBL3103334 | 0.88 | MC5R (0.55) | MAPTMC5RMC1RMEN1KMT2A | |
| SCHEMBL3094241 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAMC5RMC1R | |
| SCHEMBL7312422 | 0.80 | ECE1 (0.56) | ECE1ANPEPIL1RNERAP2ERAP1 | |
| SCHEMBL2989565 | 0.80 | ALOX15 (0.60) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL2989562 | 0.80 | ALOX15 (0.60) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL3101483 | 0.78 | KCNT1 (0.55) | ALOX15 | |
| SCHEMBL3100866 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3100693 | 0.76 | ERAP1 (0.54) | ECE1ANPEPIL1RNERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |