Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 2/20 | 0.55 |
| ▸ | MC1R | Q01726 | 2/20 | 0.55 |
| ▸ | ECE1 | P42892 | 2/20 | 0.55 |
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.50 |
| ▸ | ITGAL | P20701 | 3/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103327 | 1.00 | MC5R (0.55) | MC5RMC1RECE1HPGDSKDM4E | |
| SCHEMBL2989565 | 0.89 | ALOX15 (0.60) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL2989562 | 0.89 | ALOX15 (0.60) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL3086291 | 0.88 | ALDH1A1 (0.49) | MC5RMC1RECE1HPGDSMAPT | |
| SCHEMBL3101483 | 0.87 | KCNT1 (0.55) | ITGB2ICAM1ITGALSMN1; SMN2ALOX15 | |
| SCHEMBL3101652 | 0.84 | ECE1 (0.53) | MC5RMC1RECE1HPGDSKDM4E | |
| SCHEMBL9026907 | 0.82 | ECE1 (0.65) | MC5RMC1RECE1HPGDSKDM4E | |
| SCHEMBL13578562 | 0.82 | ECE1 (0.62) | MC5RMC1RECE1HPGDSKDM4E | |
| SCHEMBL27923213 | 0.81 | KCNT1 (0.66) | MC5RMC1RECE1KDM4EMAPT | |
| SCHEMBL901464 | 0.81 | KCNT1 (0.66) | MC5RMC1RECE1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |