Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098107 | 1.00 | FDPS (0.42) | FDPSMETAP1LAP3ANPEPCA1 | |
| SCHEMBL4341296 | 0.85 | LAP3 (0.40) | FDPSMETAP1LAP3ANPEPCA1 | |
| SCHEMBL3098289 | 0.83 | MME (0.32) | — | |
| SCHEMBL2989561 | 0.83 | FDPS (0.43) | FDPSMETAP1CA2 | |
| SCHEMBL3098286 | 0.83 | MME (0.32) | — | |
| SCHEMBL2989560 | 0.83 | FDPS (0.43) | FDPSMETAP1CA2 | |
| SCHEMBL3090768 | 0.82 | METAP2 (0.33) | FDPSMETAP1 | |
| SCHEMBL3090764 | 0.82 | METAP2 (0.33) | FDPSMETAP1 | |
| SCHEMBL3098192 | 0.81 | ENPEP (0.33) | — | |
| SCHEMBL2991077 | 0.81 | KMT2A (0.35) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |