Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PEPD | P12955 | 2/20 | 0.33 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406562 | 0.79 | KLK5 (0.46) | PEPDXPNPEP1POLBHSD17B10PREP | |
| SCHEMBL30517412 | 0.78 | ACE (0.47) | PEPDMAPTRAB9AHSD17B10 | |
| SCHEMBL10779423 | 0.76 | ACE (0.43) | PEPDXPNPEP1MAPTHSD17B10 | |
| SCHEMBL6234399 | 0.76 | HSD17B10 (0.39) | HRH3MAPK1FKBP1AHSD17B10PREP | |
| SCHEMBL7328713 | 0.76 | HSD17B10 (0.49) | NPC1HSD17B10 | |
| SCHEMBL17955686 | 0.76 | HSD17B10 (0.44) | HRH3PEPDXPNPEP1MAPTPOLB | |
| SCHEMBL10779336 | 0.75 | ACE (0.42) | PEPDXPNPEP1MAPTHSD17B10KLK5 | |
| SCHEMBL10768669 | 0.73 | HSD17B10 (0.42) | HRH3PEPDXPNPEP1NPC1MAPT | |
| SCHEMBL7323258 | 0.73 | DPP4 (0.50) | HRH3PEPDXPNPEP1MAPTHSD17B10 | |
| SCHEMBL7270677 | 0.73 | HSD17B10 (0.42) | HRH3PEPDXPNPEP1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4570813-A1 | METHOD FOR PRODUCING N-SUBSTITUTED AMINO ACID RESIDUE-CONTAINING CYCLIC PEPTIDE COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024080333-A1 | METHOD FOR PRODUCING N-SUBSTITUTED AMINO ACID RESIDUE-CONTAINING CYCLIC PEPTIDE COMPOUND | 中外製薬株式会社 | 2024-04-18 | — | — | WO | disclosed |