SCHEMBL6234399

SCHEMBL6234399

CC(C)(C)OC(=O)C1CCN1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
MAPK1 P28482 1/20 0.36
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
ROCK2 O75116 1/20 0.35
HPGD P15428 1/20 0.35
BTK Q06187 1/20 0.35
PREP P48147 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
FKBP1A P62942 2/20 0.34
GPR119 Q8TDV5 1/20 0.34
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL750515 0.89 HSD17B10 (0.50) HSD17B10ROCK2SMN1; SMN2FKBP1A
SCHEMBL11932167 0.89 HSD17B10 (0.50) HSD17B10ROCK2SMN1; SMN2FKBP1A
SCHEMBL4154856 0.88 FKBP1A (0.47) HSD17B10ROCK2HPGDSMN1; SMN2FKBP1A
SCHEMBL540702 0.88 FKBP1A (0.47) HSD17B10ROCK2HPGDSMN1; SMN2FKBP1A
SCHEMBL5517111 0.88 FKBP1A (0.47) HSD17B10ROCK2HPGDSMN1; SMN2FKBP1A
SCHEMBL7328713 0.85 HSD17B10 (0.49) HSD17B10CHRM2CHRM1CHRM3HPGD
SCHEMBL27410636 0.84 HSD17B10 (0.52) HSD17B10ROCK2PREPSMN1; SMN2FKBP1A
SCHEMBL27761053 0.81 SMN1; SMN2 (0.34) HSD17B10HRH3CHRM2CHRM1CHRM3
SCHEMBL9949884 0.80 CHRM2 (0.38) HSD17B10HRH3MAPK1CHRM2CHRM1
SCHEMBL22152560 0.80 HRH3 (0.35) HSD17B10HRH3MAPK1CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250232-A1 AZETIDINE DERIVATIVES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2025-08-07 US disclosed
WO-2024008680-A1 AZETIDINE DERIVATIVES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-01-11 WO disclosed
US-6927290-B2 Production of mixed acid anhydride and amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-08-09 US disclosed
EP-1160236-B1 Production of mixed acid anhydride and amine compound SUMITOMO CHEMICAL CO (JP) 2005-05-25 EP disclosed
US-20040210059-A1 Production of mixed acid anhydride and amide compound SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed
US-6753431-B2 REACTING A CARBAMATE DERIVATIVE WITH CARBOXYLIC AND HALOFORMIC ACID DERIVATIVES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-06-22 US disclosed
US-20020032346-A1 Production of mixed acid anhydride and amide compound SUMITOMO CHEMICAL CO., LTD. 2002-03-14 US disclosed
EP-1160236-A2 Production of mixed acid anhydride and amine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-05 EP disclosed
WO-2001034150-A1 ALIPHATIC AMINE SUBSTITUTED PIPERIDYL DIARYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS MERCK & CO., INC. (US) 2001-05-17 WO disclosed
EP-1089989-A1 INHIBITORS OF ALPHA4BETA1 MEDIATED CELL ADHESION PHARMACIA & UPJOHN COMPANY (US) 2001-04-11 EP disclosed
WO-1999067230-A1 INHIBITORS OF α4β1 MEDIATED CELL ADHESION PHARMACIA & UPJOHN COMPANY (US) 1999-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040210059-A1 Production of mixed acid anhydride and amide compound CA2, CA1, CA3 HSD17B10 2385/4885HRH3 330/4885MAPK1 1266/4885
US-20020032346-A1 Production of mixed acid anhydride and amide compound CA2, CA1, CA3 HSD17B10 2385/4885HRH3 330/4885MAPK1 1266/4885
US-20250250232-A1 AZETIDINE DERIVATIVES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS DPP9, DPP4, DPP3 HSD17B10 2261/4885HRH3 1772/4885MAPK1 2195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.