Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475243 | 0.94 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HTR2CLMNA | |
| SCHEMBL8148649 | 0.84 | TAAR1 (0.48) | TAAR1 | |
| SCHEMBL16191057 | 0.82 | TAAR1 (0.47) | TAAR1 | |
| SCHEMBL3966077 | 0.82 | GBA1 (0.56) | SLC6A4SLC6A2SLC6A3HTR2CLMNA | |
| SCHEMBL16191827 | 0.81 | ACHE (0.51) | SLC6A4TAAR1 | |
| SCHEMBL9386979 | 0.80 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3GBA1HRH3 | |
| Hydrochloric Acid SCHEMBL27158131 | 0.80 | KMT2A (0.48) | SLC6A4SLC6A2SLC6A3LMNACYP2D6 | |
| SCHEMBL1475594 | 0.79 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HTR2CGBA1 | |
| SCHEMBL19265565 | 0.79 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3GBA1TAAR1 | |
| SCHEMBL16056162 | 0.79 | GNAI3 (0.55) | SLC6A4SLC6A2HTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799787-B2 | Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase | MERCK FROSST CANADA LTD. (CA) | 2010-09-21 | — | — | US | disclosed |
| US-20090088431-A1 | Heteroaromatic Compounds as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | MERCK FROSST CANADA LTD. | 2009-04-02 | — | — | US | disclosed |
| EP-1966183-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | Merck Frosst Canada Ltd. (CA) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071023-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2007-06-28 | — | — | WO | disclosed |
| EP-1790639-A1 | COMPOUND CONTAINING BASIC GROUP AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088431-A1 | Heteroaromatic Compounds as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | SCD, SCD5, SREBF1 | SLC6A4 4324/4885SLC6A2 4429/4885SLC6A3 4305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.