Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621298 | 0.87 | ALDH1A1 (0.42) | LMNAALDH1A1MYCGAAHSD17B10 | |
| SCHEMBL31571141 | 0.84 | ALDH1A1 (0.48) | LMNAALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL30864276 | 0.84 | ALDH1A1 (0.48) | LMNAALDH1A1GAAHSD17B10ALOX15 | |
| SCHEMBL6306963 | 0.80 | LMNA (0.43) | LMNAALDH1A1MYCGAAHPGD | |
| SCHEMBL21932471 | 0.78 | LMNA (0.40) | LMNAALDH1A1MYCGAAHSD17B10 | |
| SCHEMBL16412922 | 0.74 | KMT2A (0.44) | SRD5A2HPGDHCAR3 | |
| SCHEMBL12193492 | 0.73 | ALDH1A1 (0.49) | LMNAALDH1A1MYCGAAHSD17B10 | |
| SCHEMBL16419121 | 0.72 | ALDH1A1 (0.38) | ALDH1A1HSD17B10ALOX15KDM4EHPGD | |
| SCHEMBL16412890 | 0.71 | SMN1; SMN2 (0.45) | ALDH1A1GAAHPGD | |
| SCHEMBL3313453 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MYCSRD5A2KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |