Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887656 | 0.88 | LMNA (0.44) | LMNANR4A1TDP1MEN1KMT2A | |
| SCHEMBL17145452 | 0.82 | GAA (0.43) | LMNATDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL9959424 | 0.81 | CA12 (0.34) | LMNATDP1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL24633616 | 0.80 | MAP4K4 (0.44) | LMNAMEN1KMT2AMAPTTHRB | |
| SCHEMBL9959674 | 0.79 | TDP1 (0.38) | LMNATDP1ALDH1A1TPMTKDM5A | |
| SCHEMBL25416955 | 0.76 | LMNA (0.58) | LMNAKMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3076452 | 0.74 | KDM5A (0.41) | LMNANR4A1TDP1MEN1KMT2A | |
| SCHEMBL10143655 | 0.74 | KDM4E (0.36) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23355414 | 0.73 | RAB9A (0.50) | LMNATDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL31066545 | 0.69 | NPC1 (0.41) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |