Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | RPA1 | P27694 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31066506 | 0.82 | TP53 (0.43) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL3813756 | 0.79 | RPA1 (0.45) | SMN1; SMN2MAPTPPP1CAAPOBEC3AAPOBEC3G | |
| SCHEMBL3811214 | 0.79 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2MAPTAPOBEC3A | |
| SCHEMBL4914133 | 0.79 | KMT2A (0.43) | NPC1RAB9APPP1CAAPOBEC3AAPOBEC3G | |
| SCHEMBL22129472 | 0.79 | MAPT (0.47) | NPC1RAB9ASMN1; SMN2MAPTRPA1 | |
| SCHEMBL4914023 | 0.76 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTPPP1CA | |
| SCHEMBL23293765 | 0.76 | KDM4E (0.43) | NPC1RAB9AAPOBEC3AAPOBEC3GRPA1 | |
| SCHEMBL17252261 | 0.76 | MARS1 (0.41) | APOBEC3AAPOBEC3GMEN1KMT2AALDH1A1 | |
| SCHEMBL30896086 | 0.73 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2MAPTPPP1CA | |
| SCHEMBL570553 | 0.71 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182447-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | VIVIDION THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |