Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162089 | 0.82 | HRH3 (0.42) | CHRNA7HRH3 | |
| SCHEMBL30864294 | 0.81 | HRH4 (0.43) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL31753410 | 0.80 | CHRNA7 (0.49) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL30864313 | 0.80 | CHRNA7 (0.49) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL28152135 | 0.79 | PARP1 (0.50) | CHRNA7HRH3HTR2AHTR2CKCNH2 | |
| SCHEMBL4949929 | 0.78 | CYP2A6 (0.41) | CHRNA7HRH3 | |
| Hydrochloric Acid SCHEMBL28334700 | 0.78 | PARP1 (0.49) | CHRNA7HRH3HTR2AHTR2CKCNH2 | |
| SCHEMBL6985432 | 0.77 | HRH3 (0.39) | CHRNA7HRH3HTR2AHTR2CKCNH2 | |
| SCHEMBL30864309 | 0.77 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL27367437 | 0.77 | DRD2 (0.52) | CHRNA7HRH3HTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |