Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 4/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25883037 | 1.00 | KCNK3 (0.43) | KCNK3KCNK9GPR119USP30OPRM1 | |
| SCHEMBL30471206 | 0.88 | JAK2 (0.48) | GPR119JAK2JAK3NAMPT | |
| SCHEMBL25878262 | 0.88 | MEN1 (0.49) | KCNK3KCNK9PDE10A | |
| SCHEMBL29466326 | 0.88 | MEN1 (0.49) | KCNK3KCNK9PDE10A | |
| SCHEMBL29466330 | 0.84 | GPR119 (0.42) | KCNK3KCNK9GPR119USP30JAK2 | |
| SCHEMBL27180231 | 0.84 | MEN1 (0.45) | KCNK3KCNK9PDE10A | |
| SCHEMBL29466310 | 0.83 | ANO1 (0.44) | GPR119USP30JAK2JAK1JAK3 | |
| SCHEMBL29466304 | 0.83 | CCNA2 (0.44) | GPR119USP30OPRM1OPRK1OGFRL1 | |
| SCHEMBL25882471 | 0.83 | CCNA2 (0.44) | GPR119USP30OPRM1OPRK1OGFRL1 | |
| SCHEMBL29484593 | 0.80 | CHRNA4 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101552-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101552-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | LANCL2, CBS, LCP2 | KCNK3 2933/4885KCNK9 3318/4885GPR119 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.