Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534133 | 1.00 | SYK (0.47) | SYKPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31646435 | 0.85 | P2RX7 (0.49) | SYKPOLBL3MBTL1KMT2ATP53 | |
| SCHEMBL2373934 | 0.82 | P2RX7 (0.43) | SYKKMT2AP2RX7MBOAT4MAOB | |
| SCHEMBL26046016 | 0.80 | P2RX7 (0.49) | NPSR1P2RX7MBOAT4MAOB | |
| SCHEMBL1135252 | 0.80 | ALDH1A1 (0.48) | POLBALDH1A1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL14677477 | 0.78 | KMT2A (0.47) | POLBALDH1A1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL22070548 | 0.78 | KMT2A (0.47) | POLBALDH1A1CYP2C9CYP2C19MAPK1 | |
| SCHEMBL30730161 | 0.78 | CYP1A2 (0.44) | POLBALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL29755971 | 0.78 | P2RX7 (0.50) | SYKCYP2C19P2RX7SMN1; SMN2MBOAT4 | |
| SCHEMBL868879 | 0.78 | P2RX7 (0.50) | SYKCYP2C19P2RX7SMN1; SMN2MBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903140-A | Imidazopyrimidines and triazolopyrimidines as A2A/A2B inhibitors | 因赛特公司 | 2024-04-19 | — | — | CN | disclosed |