Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24826757 | 0.79 | LMNA (0.32) | LMNA | |
| SCHEMBL30164827 | 0.79 | LMNA (0.32) | LMNA | |
| SCHEMBL23578775 | 0.79 | LMNA (0.33) | LMNA | |
| SCHEMBL24826762 | 0.77 | LMNA (0.36) | LMNA | |
| SCHEMBL24970591 | 0.72 | LMNA (0.35) | SMN1; SMN2LMNA | |
| SCHEMBL30865638 | 0.72 | — | — | |
| SCHEMBL21872085 | 0.72 | CHEK1 (0.37) | SMN1; SMN2LMNACHEK1AURKA | |
| SCHEMBL30865632 | 0.71 | KAT2B (0.36) | — | |
| SCHEMBL24811604 | 0.71 | KAT2B (0.36) | — | |
| SCHEMBL30164490 | 0.71 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916232-A | Heterocyclic EGFR inhibitors for the treatment of cancer | 缆图药品公司 | 2024-04-19 | — | — | CN | disclosed |