Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 2/20 | 0.47 |
| ▸ | CCNC | P24863 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865830 | 0.80 | MOK (0.63) | MOKCNR2TRPV1RAB9AALDH1A1 | |
| SCHEMBL30865848 | 0.74 | RAB9A (0.44) | AAK1MKNK2RAB9AKDM4EALDH1A1 | |
| SCHEMBL23214090 | 0.67 | GSPT1 (0.53) | CNR2CNR1HRH3KDM4EALDH1A1 | |
| SCHEMBL14206965 | 0.65 | CNR2 (0.72) | CNR2CNR1FTO | |
| SCHEMBL19475600 | 0.64 | MOK (1.00) | MOK | |
| SCHEMBL11181809 | 0.64 | TP53 (0.58) | AAK1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL23240214 | 0.62 | GSPT1 (0.49) | CNR2CNR1TRPV1HRH3KDM4E | |
| SCHEMBL29716298 | 0.62 | GSPT1 (0.49) | CNR2CNR1TRPV1HRH3KDM4E | |
| SCHEMBL22500270 | 0.62 | POLB (0.76) | CNR1RAB9AALDH1A1 | |
| SCHEMBL31053446 | 0.61 | NPC1 (0.56) | RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917402-A | Isoindolylamide compound, and pharmaceutical composition and application thereof | 暨南大学 | 2024-04-23 | — | — | CN | disclosed |