Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865839 | 0.74 | MOK (0.47) | RAB9AAAK1ALDH1A1KDM4EHPGD | |
| SCHEMBL11181809 | 0.72 | TP53 (0.58) | RAB9AAAK1ALDH1A1KDM4EHPGD | |
| SCHEMBL11182466 | 0.69 | CYP3A4 (0.63) | RAB9AALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL30865830 | 0.68 | MOK (0.63) | RAB9AALDH1A1CYP3A4NPC1CYP2D6 | |
| SCHEMBL334233 | 0.66 | BCHE (0.61) | RAB9AALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL6456112 | 0.63 | MAPT (0.58) | RAB9AALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL21765857 | 0.63 | RAB9A (1.00) | RAB9AAAK1ALDH1A1KDM4EHPGD | |
| SCHEMBL11178746 | 0.62 | AAK1 (0.55) | RAB9AAAK1ALDH1A1NPC1POLB | |
| SCHEMBL10532453 | 0.62 | ABL1 (0.49) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL8589404 | 0.62 | GSTO1 (0.50) | RAB9AALDH1A1KDM4ECYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917402-A | Isoindolylamide compound, and pharmaceutical composition and application thereof | 暨南大学 | 2024-04-23 | — | — | CN | disclosed |