Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202429 | 0.84 | GRM5 (0.49) | PDK2HDAC1ESR2GPR119SLC6A9 | |
| SCHEMBL23015352 | 0.84 | HDAC1 (0.45) | MAPK1PDK2HDAC1ESR2GPR119 | |
| SCHEMBL29240214 | 0.83 | MAPT (0.43) | MAPTLMNAPDK2SMN1; SMN2HTT | |
| SCHEMBL28967185 | 0.82 | PDK2 (0.42) | MAPK1PDK2HDAC1ESR2GPR119 | |
| SCHEMBL21525539 | 0.81 | PDK2 (0.44) | MAPTPDK2HDAC1ESR2GPR119 | |
| SCHEMBL18883091 | 0.81 | PDK2 (0.41) | MAPK1PDK2HDAC1ESR2SMN1; SMN2 | |
| SCHEMBL23015254 | 0.79 | USP30 (0.44) | MAPTALDH1A1LMNAMAPK1PDK2 | |
| SCHEMBL30834648 | 0.79 | GPR119 (0.44) | MAPTALDH1A1LMNAPDK2HDAC1 | |
| SCHEMBL30866131 | 0.78 | LMNA (0.57) | MAPTALDH1A1LMNAPDK2ESR2 | |
| SCHEMBL30899238 | 0.77 | SLC34A1 (0.45) | PDK2HDAC1ESR2NR1H2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917415-A | Substituted heteropolycyclic compound, preparation method and application thereof | 映恩生物制药（苏州）有限公司 | 2024-04-23 | — | — | CN | disclosed |