Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 9/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202429 | 0.88 | GRM5 (0.49) | SLC34A1SLC6A9KCNH2HPGDSHDAC1 | |
| SCHEMBL23015352 | 0.81 | HDAC1 (0.45) | SLC34A1SLC6A9HDAC1GRM5GRM1 | |
| SCHEMBL29262509 | 0.81 | SLC6A9 (0.41) | SLC6A9KCNH2PDK2 | |
| SCHEMBL28967185 | 0.79 | PDK2 (0.42) | SLC34A1SLC6A9KCNH2HDAC1GRM5 | |
| SCHEMBL21525539 | 0.78 | PDK2 (0.44) | SLC34A1HDAC1PDK2ESR2NR1H2 | |
| SCHEMBL20792753 | 0.78 | PDK2 (0.56) | SLC34A1HPGDSGRM5GRM1PDK2 | |
| SCHEMBL18883091 | 0.78 | PDK2 (0.41) | SLC34A1SLC6A9HDAC1GRM5GRM1 | |
| SCHEMBL30866165 | 0.77 | MAPT (0.57) | SLC34A1SLC6A9KCNH2HDAC1PDK2 | |
| SCHEMBL18376191 | 0.77 | NR1H2 (0.46) | HDAC1ESR2NR1H2 | |
| SCHEMBL30834648 | 0.76 | GPR119 (0.44) | SLC34A1HDAC1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754635-B | Condensed ring compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2024-06-21 | — | — | CN | disclosed |