Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 4/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21512509 | 1.00 | MET (0.43) | METRORCLRRK2SLC6A4HTR6 | |
| SCHEMBL7469167 | 0.86 | LRRK2 (0.43) | METRORCLRRK2SLC6A4HTR6 | |
| SCHEMBL26916934 | 0.82 | MET (0.55) | METRORCLRRK2JAK2NUDT1 | |
| SCHEMBL26916614 | 0.82 | MET (0.55) | METRORCLRRK2JAK2NUDT1 | |
| SCHEMBL29857651 | 0.82 | MET (0.55) | METRORCLRRK2JAK2NUDT1 | |
| SCHEMBL29858073 | 0.82 | MET (0.55) | METRORCLRRK2JAK2NUDT1 | |
| SCHEMBL10215048 | 0.82 | MET (0.55) | METRORCLRRK2JAK2NUDT1 | |
| SCHEMBL31065340 | 0.79 | RORC (0.61) | METRORCLRRK2SLC6A4HTR6 | |
| SCHEMBL30866857 | 0.79 | MET (0.41) | METS1PR3S1PR1 | |
| SCHEMBL21512505 | 0.79 | MET (0.41) | METS1PR3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469720-B | Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy | 艾科思莱德制药公司 | 2024-03-29 | — | — | CN | disclosed |