Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21512505 | 1.00 | MET (0.41) | METHRH4CSNK2A1S1PR1S1PR3 | |
| SCHEMBL1622023 | 0.82 | MET (0.37) | METS1PR1S1PR3 | |
| SCHEMBL856112 | 0.81 | MET (0.38) | METS1PR1S1PR3 | |
| SCHEMBL2067656 | 0.79 | PIK3C3 (0.41) | METHRH4S1PR1S1PR3GABRA1 | |
| SCHEMBL21512509 | 0.79 | MET (0.43) | METS1PR1S1PR3 | |
| SCHEMBL30866876 | 0.79 | MET (0.43) | METS1PR1S1PR3 | |
| SCHEMBL27020347 | 0.79 | ALDH1A1 (0.38) | MET | |
| SCHEMBL30366269 | 0.79 | CHRNB2 (0.42) | — | |
| SCHEMBL608749 | 0.79 | CHRNB2 (0.42) | — | |
| SCHEMBL23034623 | 0.78 | CSNK2A1 (0.34) | CSNK2A1S1PR1S1PR3KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469720-B | Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy | 艾科思莱德制药公司 | 2024-03-29 | — | — | CN | disclosed |