SCHEMBL30867003

SCHEMBL30867003

CC(C)C(=O)OC[C@H]1CC[C@@](C#N)(n2ccc(N)nc2=O)O1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
POLA1 P09884 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13470533 0.79 PDE3A (0.31)
SCHEMBL27086534 0.76 LMNA (0.35) POLA1
SCHEMBL27086497 0.73 POLA1 (0.31) POLA1
SCHEMBL27086462 0.73 POLA1 (0.30) POLA1
SCHEMBL10511557 0.71 LMNA (0.47) POLA1
SCHEMBL20117255 0.71 LMNA (0.47) POLA1
SCHEMBL30867005 0.69 MAPT (0.33)
SCHEMBL21100416 0.68 PDE3A (0.45) FGFR1SLC22A6
SCHEMBL21099800 0.68 PDE3A (0.36) FGFR1SLC22A6
SCHEMBL9755546 0.67 POLA1 (0.35) FGFR1SLC22A6POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858711-A Nucleoside and nucleotide analogs as antiviral agents 爱莫里大学 2024-04-09 CN disclosed