Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | POLG | P54098 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755570 | 0.73 | POLA1 (0.39) | POLA1POLGPOLBFGFR1SLC22A6 | |
| SCHEMBL8673536 | 0.71 | POLG (0.51) | POLA1POLGPOLBP2RY2 | |
| SCHEMBL30612477 | 0.69 | LMNA (0.41) | POLBFGFR1SLC22A6PDE3ACACNA1F | |
| SCHEMBL8104294 | 0.69 | LMNA (0.41) | POLBFGFR1SLC22A6PDE3ACACNA1F | |
| SCHEMBL17027931 | 0.68 | POLB (0.46) | POLA1POLGPOLBPDE3AST6GAL1 | |
| SCHEMBL4745588 | 0.68 | PDE3A (0.45) | POLA1POLGPOLBFGFR1SLC22A6 | |
| SCHEMBL5903747 | 0.68 | LMNA (0.40) | POLBFGFR1SLC22A6PDE3ACACNA1F | |
| SCHEMBL30867003 | 0.67 | FGFR1 (0.31) | POLA1FGFR1SLC22A6 | |
| SCHEMBL24872399 | 0.66 | LMNA (0.49) | POLA1POLGPOLBPDE3ACACNA1F | |
| SCHEMBL15259219 | 0.66 | LMNA (0.49) | POLA1POLGPOLBPDE3ACACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019727-A1 | 5'-HYDROGENPHOSPHONATES AND 5'-METHYLPHOSPHONATES OF SUGAR MODIFIED NUCLEOSIDES, COMPOSITIONS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-12-26 | — | — | WO | disclosed |