Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446400 | 1.00 | RAPGEF4 (0.43) | RAPGEF4HDAC4ACHEPTGS1PTGS2 | |
| SCHEMBL12446940 | 0.84 | RAPGEF4 (0.42) | RAPGEF4ACHEPTGS1PTGS2HDAC1 | |
| SCHEMBL67360 | 0.84 | RAPGEF4 (0.42) | RAPGEF4HDAC4ACHEPTGS1PTGS2 | |
| SCHEMBL97078 | 0.77 | RAPGEF4 (0.43) | RAPGEF4ACHEPTGS1PTGS2CES2 | |
| SCHEMBL1056730 | 0.77 | RAPGEF4 (0.43) | RAPGEF4ACHEHDAC1HDAC6ALDH1A1 | |
| SCHEMBL31633777 | 0.77 | RAPGEF4 (0.43) | RAPGEF4ACHEHDAC1HDAC6ALDH1A1 | |
| Boric Acid SCHEMBL17967033 | 0.74 | HDAC1 (0.41) | RAPGEF4HDAC4PTGS1PTGS2HDAC1 | |
| SCHEMBL8847064 | 0.73 | ACHE (0.35) | RAPGEF4ACHEHDAC1HDAC6TUBB1 | |
| SCHEMBL24699771 | 0.72 | TTR (0.32) | ACHEHDAC1HDAC6 | |
| SCHEMBL12121733 | 0.72 | RAPGEF4 (0.35) | RAPGEF4HDAC4HDAC1HDAC6CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964544-A | Synthetic method of isoindoline derivatives | 上海吉奉生物科技有限公司 | 2024-05-03 | — | — | CN | disclosed |