SCHEMBL97078

SCHEMBL97078

Cc1cc(F)cc(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 3/20 0.43
CES2 O00748 4/20 0.42
CES1 P23141 4/20 0.42
ACHE P22303 3/20 0.33
PTGS1 P23219 2/20 0.33
PTGS2 P35354 2/20 0.33
RIPK1 Q13546 3/20 0.32
ALDH1A1 P00352 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13550041 0.84 RAPGEF4 (0.37) RAPGEF4CES2CES1ACHEPTGS1
SCHEMBL531337 0.77 CES2 (0.52) RAPGEF4CES2CES1RIPK1ALDH1A1
SCHEMBL8446400 0.77 RAPGEF4 (0.43) RAPGEF4CES2CES1ACHEPTGS1
SCHEMBL30867014 0.77 RAPGEF4 (0.43) RAPGEF4CES2CES1ACHEPTGS1
SCHEMBL8268053 0.77 RAPGEF4 (0.52) RAPGEF4ACHEALDH1A1CA1
Chloromethane SCHEMBL27844640 0.75 CES2 (0.46) RAPGEF4CES2CES1RIPK1ALDH1A1
SCHEMBL30567470 0.73 RAPGEF4 (0.38) RAPGEF4CES2CES1ACHE
SCHEMBL823681 0.73 RAPGEF4 (0.38) RAPGEF4CES2CES1ACHE
SCHEMBL24369309 0.72 RAPGEF4 (0.31) RAPGEF4PTGS1PTGS2
SCHEMBL11992628 0.72 RAPGEF4 (0.34) RAPGEF4ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1696 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260058204-A1 ELECTROLYTE COMPOSITION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY CONTAINING THE SAME HYUNDAI MOTOR CO LTD (KR) 2026-02-26 US claimed
EP-1267906-A1 LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION Bristol-Myers Squibb Pharma Company (US) 2003-01-02 EP claimed
US-6495540-B2 HEXAHYDROAZEPINE-2-ONE DERIVATIVE AS BETA-AMYLOID INHIBITOR BRISTOL - MYERS SQUIBB PHARMA COMPANY 2002-12-17 US claimed
US-20020010172-A1 Lactams as inhibitors of A-beta protein production BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-01-24 US claimed
WO-2001072324-A1 LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2001-10-04 WO claimed
EP-4283734-B1 ELECTROLYTE FOR RECHARGEABLE LITHIUM BATTERY AND RECHARGEABLE LITHIUM BATTERY INCLUDING SAME SAMSUNG SDI CO LTD (KR) 2026-05-20 EP disclosed
US-12633526-B2 Electrode for rechargeable lithium battery and rechargeable lithium battery including same SAMSUNG SDI CO., LTD. (KR) 2026-05-19 US disclosed
CN-115911298-B Positive electrode active material, method of preparing the same, and rechargeable lithium battery including the same 三星SDI株式会社 2026-05-15 CN disclosed
US-12626902-B2 Electrode for rechargeable lithium battery, electrode assembly and rechargeable lithium battery including the same SAMSUNG SDI CO., LTD. (KR) 2026-05-12 US disclosed
EP-4080610-B1 A MANUFACTURING METHOD OF A NEGATIVE ACTIVE MATERIAL FOR A LITHIUM SECONDARY BATTERY, A NEGATIVE ACTIVE MATERIAL FOR A LITHIUM SECONDARY BATTERY, AND A LITHIUM SECONDARY BATTERY CONTAINING THIS NEGATIVE ACTIVE MATERIAL POSCO (KR) 2026-05-06 EP disclosed
EP-4228025-B1 NEGATIVE ELECTRODE FOR RECHARGEABLE LITHIUM BATTERY AND RECHARGEABLE LITHIUM BATTERY INCLUDING SAME SAMSUNG SDI CO LTD (KR) 2026-05-06 EP disclosed
EP-4163994-B1 NEGATIVE ELECTRODE FOR RECHARGEABLE LITHIUM BATTERY AND RECHARGEABLE LITHIUM BATTERY INCLUDING SAME SAMSUNG SDI CO LTD (KR) 2026-05-06 EP disclosed
WO-2001072324-A1 LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2001-10-04 WO disclosed
US-20010020034-A1 Isothiazole derivatives useful as anticancer agents PFIZER, INC. 2001-09-06 US disclosed
US-6235764-B1 Isothiazole derivatives useful as anticancer agents PFIZER INC. 2001-05-22 US disclosed
WO-2000039088-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2000-07-06 WO disclosed
US-6057480-A Process for preparing fluoroaryl magnesium derivative and process for preparing (fluoroaryl) borane compound NIPPON SHOKUBAI CO., LTD. (JP) 2000-05-02 US disclosed
EP-0838466-A2 Producing process of (fluoroaryl) borane compound and producing process of tetrakis (fluoroaryl) borate derivative NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-29 EP disclosed
EP-0825195-A1 PROCESS FOR THE PREPARATION OF FLUORINATED ARYLMAGNESIUM DERIVATIVES AND PROCESS FOR THE PREPARATION OF (FLUORINATED ARYL)BORON COMPOUNDS NIPPON SHOKUBAI CO., LTD. (JP) 1998-02-25 EP disclosed
EP-0394644-A2 Halobenzene derivatives BAYER AG (DE) 1990-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12633526-B2 Electrode for rechargeable lithium battery and rechargeable lithium battery including same CACNA2D2, CACNA2D4, CACNA2D1 RAPGEF4 2209/4885CES2 2077/4885CES1 3917/4885
US-20010020034-A1 Isothiazole derivatives useful as anticancer agents TP53, MCL1, ACIN1 RAPGEF4 3832/4885CES2 2476/4885CES1 283/4885
US-20260058204-A1 ELECTROLYTE COMPOSITION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY CONTAINING THE SAME KCNN2, DYRK1B, SETDB1 RAPGEF4 3674/4885CES2 2767/4885CES1 4595/4885
US-12626902-B2 Electrode for rechargeable lithium battery, electrode assembly and rechargeable lithium battery including the same SLC9A2, SLC9A1, SLC9B2 RAPGEF4 1828/4885CES2 624/4885CES1 2408/4885
US-20020010172-A1 Lactams as inhibitors of A-beta protein production BACE1, APP, APH1A RAPGEF4 2254/4885CES2 1767/4885CES1 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.