SCHEMBL30867172

SCHEMBL30867172

Cn1cc(-c2nc(OCCc3c[nH]c4ccccc34)c3ncsc3n2)cn1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ABCC1 P33527 2/20 0.36
ABCB1 P08183 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
SSTR2 P30874 1/20 0.36
SSTR4 P31391 1/20 0.36
KIT P10721 1/20 0.36
GSK3B P49841 1/20 0.35
NEK4 P51957 1/20 0.35
CSNK2A1 P68400 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
HTR1A P08908 6/20 0.35
HTR2A P28223 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HTT P42858 1/20 0.35
PRKCI P41743 1/20 0.35
GBA1 P04062 1/20 0.35
EIF2AK2 P19525 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27319560 1.00 ABCC1 (0.36) ABCC1ABCB1ABCG2SSTR2SSTR4
SCHEMBL30867162 0.88 HTR1A (0.39) HTR1AHTR2A
SCHEMBL27321120 0.88 MPO (0.40) HTR1AHTR2A
SCHEMBL27319874 0.88 HTR1A (0.39) HTR1AHTR2A
SCHEMBL30867133 0.88 MPO (0.40) HTR1AHTR2A
SCHEMBL27319556 0.86 HTR1A (0.41) KITHTR1AHTR2AKDM4EALDH1A1
SCHEMBL31534056 0.84 GBA1 (0.41) SSTR2SSTR4GSK3BNEK4CSNK2A1
SCHEMBL30867195 0.84 PTGS2 (0.40) SSTR2SSTR4GSK3BNEK4CSNK2A1
SCHEMBL27319333 0.84 PTGS2 (0.40) SSTR2SSTR4GSK3BNEK4CSNK2A1
SCHEMBL31534073 0.83 CDK4 (0.43) SSTR2SSTR4GSK3BHTR1APRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598931-A1 COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING JAGUAHR THERAPEUTICS PTE LTD (SG) 2025-08-13 EP disclosed
CN-119948035-A Compounds useful for modulating AhR signaling 捷豹治疗有限公司 2025-05-06 CN disclosed
WO-2024076300-A1 COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING JAGUAHR THERAPEUTICS PTE LTD (SG) 2024-04-11 WO disclosed