Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.68 |
| ▸ | HTR6 | P50406 | 2/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750432 | 0.84 | HTR6 (0.68) | HTR7HTR6ADRA2AADRA2BADRA2C | |
| SCHEMBL23657217 | 0.83 | HTR6 (0.67) | HTR7HTR6ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL892350 | 0.83 | HTR6 (0.67) | HTR7HTR6ADRA2AADRA2BADRA2C | |
| SCHEMBL18509842 | 0.82 | ADRA2A (0.62) | HTR7HTR6ADRA2AADRA2BADRA2C | |
| SCHEMBL24358704 | 0.81 | HTR6 (0.65) | HTR7HTR6ADRA2AADRA2BADRA2C | |
| SCHEMBL1817642 | 0.81 | HTR6 (1.00) | HTR7HTR6ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL23649325 | 0.81 | HTR6 (0.65) | HTR7HTR6ADRA2AADRA2BADRA2C | |
| SCHEMBL23612421 | 0.81 | ALDH1A1 (0.61) | HTR7HTR6ADRA2AADRA2BADRA2C | |
| SCHEMBL31534095 | 0.81 | ALDH1A1 (0.61) | HTR7HTR6ADRA2AADRA2BADRA2C | |
| Cyanide SCHEMBL28561199 | 0.80 | HTR6 (0.63) | HTR7HTR6ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598931-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-08-13 | — | — | EP | disclosed |
| CN-119948035-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |