Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30867700 | 0.90 | — | — | |
| SCHEMBL30867882 | 0.85 | HTR1A (0.36) | — | |
| SCHEMBL30868059 | 0.81 | SSTR1 (0.36) | PLG | |
| SCHEMBL30867883 | 0.81 | TLR8 (0.33) | — | |
| SCHEMBL30867858 | 0.77 | HTR2A (0.31) | — | |
| SCHEMBL38654423 | 0.77 | HTR2A (0.31) | — | |
| SCHEMBL38653853 | 0.75 | PDE10A (0.34) | PLG | |
| SCHEMBL30867758 | 0.73 | GPR119 (0.38) | — | |
| SCHEMBL38653881 | 0.69 | RAF1 (0.32) | — | |
| SCHEMBL30867920 | 0.69 | GPR119 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598917-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | Amgen Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076674-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2024-04-11 | — | — | WO | disclosed |