Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | AHR | P35869 | 4/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921056 | 0.81 | DYRK1A (0.58) | KDM4EMEN1KMT2ADYRK1APDE10A | |
| SCHEMBL756100 | 0.81 | KDM4E (0.50) | KDM4EDYRK1APDE10ASMN1; SMN2AHR | |
| SCHEMBL26373829 | 0.78 | DYRK1A (0.42) | KDM4EMEN1KMT2ADYRK1APDE10A | |
| SCHEMBL7895997 | 0.76 | DYRK1A (0.41) | KDM4EMEN1KMT2ADYRK1ANPC1 | |
| SCHEMBL7889606 | 0.76 | DYRK1A (0.41) | KDM4EMEN1KMT2ADYRK1ANPC1 | |
| SCHEMBL25104909 | 0.76 | DYRK1A (0.41) | KDM4EMEN1KMT2ADYRK1APDE10A | |
| SCHEMBL12673757 | 0.76 | DYRK1A (0.41) | KDM4EMEN1KMT2ADYRK1ANPC1 | |
| SCHEMBL477109 | 0.76 | DYRK1A (0.53) | KDM4EMEN1KMT2ADYRK1APDE10A | |
| SCHEMBL2066163 | 0.76 | PDE10A (0.50) | KDM4EDYRK1APDE10AAHRDRD2 | |
| SCHEMBL3342789 | 0.76 | PDE10A (0.39) | KDM4EDYRK1APDE10AAHRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10870638-B2 | Pyridazinone compound or its salt, and herbicide containing it | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2020-12-22 | — | — | US | disclosed |
| US-20200172517-A1 | PYRIDAZINONE COMPOUND OR ITS SALT, AND HERBICIDE CONTAINING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-8946222-B2 | Phenoxymethyl heterocyclic compounds | FORUM PHARMACEUTICALS INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20130143888-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | ENVIVO PHAMACEUTICALS, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| EP-1930331-B1 | METHOD FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2013-03-13 | — | — | EP | disclosed |
| US-8334379-B2 | Process for producing imidazo[1,2-b]pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20100234597-A1 | PROCESS FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-1930331-A1 | METHOD FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10870638-B2 | Pyridazinone compound or its salt, and herbicide containing it | H1-0, H1-4, H1-3 | KDM4E 1092/4885MEN1 4130/4885KMT2A 313/4885 |
| US-20130143888-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | PDE3A, PDE2A, PDE5A | KDM4E 559/4885MEN1 1513/4885KMT2A 1618/4885 |
| US-20100234597-A1 | PROCESS FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | CYP1B1, CYP4Z1, CYP2J2 | KDM4E 2589/4885MEN1 3138/4885KMT2A 1643/4885 |
| US-20200172517-A1 | PYRIDAZINONE COMPOUND OR ITS SALT, AND HERBICIDE CONTAINING IT | H1-0, H1-4, H1-3 | KDM4E 1092/4885MEN1 4130/4885KMT2A 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.