Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | AHR | P35869 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053018 | 0.84 | DYRK1A (0.41) | DYRK1AKDM4ECOMTDRD2DRD4 | |
| SCHEMBL756100 | 0.81 | KDM4E (0.50) | DYRK1AKDM4EDRD2DRD4DRD3 | |
| SCHEMBL3921056 | 0.81 | DYRK1A (0.58) | DYRK1AKDM4ECOMTSMN1; SMN2NPC1 | |
| SCHEMBL6623486 | 0.76 | KDM4E (0.46) | DYRK1AKDM4EDRD2DRD4DRD3 | |
| SCHEMBL19086949 | 0.76 | KDM4E (0.46) | DYRK1AKDM4EDRD2DRD4DRD3 | |
| SCHEMBL20033886 | 0.76 | KDM4E (0.46) | DYRK1AKDM4EDRD2DRD4DRD3 | |
| SCHEMBL3086869 | 0.76 | KDM4E (0.44) | DYRK1AKDM4ECOMTDRD2DRD4 | |
| SCHEMBL3357291 | 0.76 | KDM4E (0.46) | KDM4EDRD2DRD4DRD3HTR1A | |
| SCHEMBL17232819 | 0.76 | DYRK1A (0.53) | DYRK1AKDM4ECOMTSMN1; SMN2NPC1 | |
| SCHEMBL16118521 | 0.76 | KDM4E (0.46) | DYRK1AKDM4EDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609731-A | Process for brominating ergot alkaloids | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | claimed |
| US-12528810-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-01-20 | — | — | US | disclosed |
| US-20260008790-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | HOFFMANN-LA ROCHE INC. (US) | 2026-01-08 | — | — | US | disclosed |
| EP-4658655-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | disclosed |
| US-20250353858-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEONE MEDICINES I GMBH (CH) | 2025-11-20 | — | — | US | disclosed |
| US-20250353841-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HUFF SARAH ELIZABETH (US) | 2025-11-20 | — | — | US | disclosed |
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| EP-4308576-B1 | NEW THIAZOLOPYRIMIDINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-04-23 | — | — | EP | disclosed |
| US-20250115569-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LTD (GB) | 2025-04-10 | — | — | US | disclosed |
| CN-119454705-A | Formulations and methods of use of RBP4 inhibitors | 倍亮生物有限责任公司 | 2025-02-18 | — | — | CN | disclosed |
| US-7307165-B2 | Process for producting imidazo[1,2-b]pyridazine derivative | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2007-12-11 | — | — | US | disclosed |
| US-7307165-B2 | Process for producting imidazo[1,2-b]pyridazine derivative | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20050171108-A1 | Novel process for producting imidazo[1,2-b]pyridazine derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-1541575-A1 | NOVEL PROCESS FOR PRODUCING IMIDAZO(1,2-B)PYRIDAZINE DERIVATIVE | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-20050032650-A1 | Fused heterocyclic sulfonylurea compound herbicide containing the same and method of controlling weed with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-02-10 | — | — | US | disclosed |
| EP-1466527-A1 | FUSED HETEROCYCLIC SULFONYLUREA COMPOUND, HERBICIDE CONTAINING THE SAME, AND METHOD OF CONTROLLING WEED WITH THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2004-10-13 | — | — | EP | disclosed |
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4609731-A | Process for brominating ergot alkaloids | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008790-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | SMN1; SMN2, RBM22, RBM17 | DYRK1A 2789/4885KDM4E 2095/4885COMT 1436/4885 |
| US-20050171108-A1 | Novel process for producting imidazo[1,2-b]pyridazine derivative | POR, CBR3, NR2C2 | DYRK1A 1821/4885KDM4E 2179/4885COMT 3482/4885 |
| US-12528810-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | CLK3, CLK2, CLK1 | DYRK1A 18/4885KDM4E 2135/4885COMT 3851/4885 |
| US-20250353841-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, ATXN2 | DYRK1A 2870/4885KDM4E 2060/4885COMT 339/4885 |
| US-20250353858-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | DGKG, DGKK, DGKA | DYRK1A 2302/4885KDM4E 2153/4885COMT 4328/4885 |
| US-20250115569-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | CACNA1A, CACNA1E, CACNA1S | DYRK1A 973/4885KDM4E 2441/4885COMT 3137/4885 |
| US-20050032650-A1 | Fused heterocyclic sulfonylurea compound herbicide containing the same and method of controlling weed with the same | NOTUM, WEE1, DDT | DYRK1A 576/4885KDM4E 683/4885COMT 2750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.