Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17418953 | 0.97 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRBHTTDNM1 | |
| Iodide SCHEMBL30869362 | 0.94 | ALDH1A1 (0.41) | ALDH1A1TSHRHTTDNM1MLNR | |
| Bromide SCHEMBL30869335 | 0.94 | ALDH1A1 (0.41) | ALDH1A1TSHRHTTDNM1MLNR | |
| SCHEMBL25834246 | 0.94 | ALDH1A1 (0.41) | ALDH1A1TSHRHTTDNM1MLNR | |
| SCHEMBL25834242 | 0.92 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBHTTDNM1 | |
| SCHEMBL25834205 | 0.87 | HTT (0.52) | ALDH1A1HTTDNM1MLNRNR1I2 | |
| SCHEMBL25834213 | 0.87 | HTT (0.52) | ALDH1A1HTTDNM1MLNRNR1I2 | |
| SCHEMBL25834209 | 0.87 | HTT (0.52) | ALDH1A1HTTDNM1MLNRNR1I2 | |
| Hydrochloric Acid SCHEMBL30869357 | 0.86 | ALDH1A1 (0.32) | ALDH1A1TSHRTHRB | |
| SCHEMBL202691 | 0.86 | DNM1 (0.40) | ALDH1A1TSHRHTTDNM1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119236538-A | Environment-friendly filter bag and preparation process thereof | 深圳市羽丰华筛网有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-117813334-A | Onium salt, blocking agent dissociation catalyst for blocking isocyanate, blocked isocyanate composition containing blocking agent dissociation catalyst, thermosetting resin composition, cured product, and method for producing same | 广荣化学株式会社 | 2024-04-02 | — | — | CN | disclosed |