SCHEMBL30869412

SCHEMBL30869412

Brc1cnc2c(c1)Oc1cc(Br)cnc1N2CCCN1CCOCC1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
EGFR P00533 4/20 0.41
KDM4E B2RXH2 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM1A O60341 3/20 0.39
TSHR P16473 1/20 0.39
TLR7 Q9NYK1 2/20 0.39
LSS P48449 1/20 0.38
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869654 0.99 ALDH1A1 (0.43) ALDH1A1EGFRKDM4ESMN1; SMN2KDM1A
SCHEMBL30869403 0.90 EGFR (0.43) EGFRKDM4ESMN1; SMN2KDM1ATSHR
SCHEMBL30869652 0.90 EGFR (0.41) ALDH1A1EGFRKDM4ESMN1; SMN2KDM1A
SCHEMBL30869487 0.89 TSHR (0.51) ALDH1A1KDM4ESMN1; SMN2TSHRLSS
SCHEMBL30869430 0.86 ALDH1A1 (0.39) ALDH1A1EGFRKDM4EKDM1ATLR7
SCHEMBL30869671 0.86 ALDH1A1 (0.41) ALDH1A1EGFRKDM4EKDM1A
SCHEMBL30869519 0.85 ALDH1A1 (0.41) ALDH1A1EGFRKDM4ESMN1; SMN2KDM1A
SCHEMBL30869590 0.83 PIM1 (0.45) ALDH1A1EGFRTSHRHTT
SCHEMBL30869530 0.79
SCHEMBL30869466 0.79 KDM4E (0.34) ALDH1A1KDM4ESMN1; SMN2TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed