SCHEMBL30869487

SCHEMBL30869487

Brc1cnc2c(c1)Oc1cc(Br)cnc1N2CCOCCN1CCOCC1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.51
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HTT P42858 2/20 0.38
MAPT P10636 1/20 0.38
LSS P48449 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869621 0.90 TSHR (0.50) TSHRALDH1A1KDM4ESMN1; SMN2HTT
SCHEMBL30869654 0.90 ALDH1A1 (0.43) TSHRALDH1A1KDM4ESMN1; SMN2HTT
SCHEMBL30869412 0.89 ALDH1A1 (0.42) TSHRALDH1A1KDM4ESMN1; SMN2HTT
SCHEMBL30869512 0.87 TSHR (0.42) TSHRALDH1A1KDM4ESMN1; SMN2
SCHEMBL30869550 0.82 TSHR (0.33) TSHR
SCHEMBL30869467 0.82
SCHEMBL30869652 0.81 EGFR (0.41) TSHRALDH1A1KDM4ESMN1; SMN2LSS
SCHEMBL30869680 0.81 TSHR (0.32) TSHR
SCHEMBL30869590 0.80 PIM1 (0.45) TSHRALDH1A1HTTMAPT
SCHEMBL30869403 0.79 EGFR (0.43) TSHRKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 TSHR 2846/4885ALDH1A1 4860/4885KDM4E 2562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.