SCHEMBL30869576

SCHEMBL30869576

CN1CCN(CCN2c3ccc(-c4ccc5[nH]ncc5c4)cc3Sc3cc(-c4ccc5[nH]ncc5c4)ccc32)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.50
ROCK2 O75116 5/20 0.44
MAP3K11 Q16584 1/20 0.44
TNIK Q9UKE5 1/20 0.44
ROCK1 Q13464 4/20 0.43
GSK3B P49841 5/20 0.43
CDK5 Q00535 4/20 0.43
DYRK1A Q13627 4/20 0.43
AURKA O14965 3/20 0.43
DAPK3 O43293 3/20 0.43
GSK3A P49840 3/20 0.43
CHEK2 O96017 2/20 0.43
CDK2 P24941 2/20 0.43
MARK3 P27448 2/20 0.43
LIMK1 P53667 2/20 0.43
PRKACA P17612 2/20 0.43
RPS6KA3 P51812 2/20 0.43
CDK1 P06493 1/20 0.43
ABCB1 P08183 1/20 0.42
CLK1 P49759 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869478 0.92 ROCK2 (0.51) KDM1AROCK2ROCK1GSK3BCDK5
SCHEMBL32682887 0.90 EGFR (0.52) KDM1AROCK2ROCK1GSK3BCDK5
SCHEMBL30869758 0.78 KDM1A (0.47) KDM1ATNIKPRKD2EGFRMAP4K4
SCHEMBL30869456 0.76 EGFR (0.53) ROCK2ROCK1GSK3BCDK5DYRK1A
SCHEMBL30869586 0.73 KDM1A (0.50) KDM1AMAP3K11ABCB1ACVR1
SCHEMBL30869756 0.72 PIK3CG (0.49) KDM1A
SCHEMBL30869720 0.72 KDM1A (0.64) KDM1AABCB1KCNH2
SCHEMBL32682882 0.71 KDM1A (0.47) KDM1ADYRK1AJAK2LRRK2
SCHEMBL30869573 0.71 EGFR (0.53) KDM1AROCK2ROCK1GSK3BCDK5
SCHEMBL30869734 0.71 EGFR (0.55) KDM1AROCK2ROCK1GSK3BCDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed