SCHEMBL30869758

SCHEMBL30869758

c1cc2c(cc1-c1cnc3[nH]ncc3c1)Sc1cc(-c3cnc4[nH]ncc4c3)ccc1N2CCN1CCOCC1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 11/20 0.47
PDE10A Q9Y233 1/20 0.42
EGFR P00533 2/20 0.42
CD274 Q9NZQ7 1/20 0.42
MAP4K4 O95819 1/20 0.42
ERBB2 P04626 1/20 0.42
MAPK9 P45984 1/20 0.42
CSNK1D P48730 1/20 0.42
PRKD2 Q9BZL6 1/20 0.42
SLK Q9H2G2 1/20 0.42
TNIK Q9UKE5 1/20 0.40
PIK3CA P42336 1/20 0.39
ULK1 O75385 1/20 0.38
PIK3C3 Q8NEB9 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32682887 0.87 EGFR (0.52) KDM1AEGFRMAP4K4ERBB2MAPK9
SCHEMBL30869745 0.86 PDE10A (0.45) PDE10AEGFRCD274MAP4K4ERBB2
SCHEMBL30869650 0.81 PIK3CD (0.47) KDM1APIK3CA
SCHEMBL30869478 0.78 ROCK2 (0.51) KDM1AEGFRMAP4K4ERBB2MAPK9
SCHEMBL30869576 0.78 KDM1A (0.50) KDM1AEGFRMAP4K4ERBB2MAPK9
SCHEMBL30869658 0.77 CHRNA7 (0.47) TNIKPIK3C3
SCHEMBL27346396 0.77 PDE10A (0.39) PDE10AEGFRCD274MAP4K4ERBB2
SCHEMBL27324454 0.76 KDM1A (0.53) KDM1ACD274
SCHEMBL30869756 0.76 PIK3CG (0.49) KDM1APIK3CA
SCHEMBL30869741 0.75 KDM1A (0.52) KDM1APIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 KDM1A 3264/4885PDE10A 2747/4885EGFR 1355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.