SCHEMBL30869404

SCHEMBL30869404

OC(CN1CC2COCC(C2)C1)CN1c2ccc(Br)cc2Oc2cc(Br)ccc21

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
MAPK1 P28482 2/20 0.33
PRMT5 O14744 2/20 0.33
WDR77 Q9BQA1 2/20 0.33
MEN1 O00255 2/20 0.33
RAD52 P43351 1/20 0.33
BAX Q07812 1/20 0.33
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
USP2 O75604 1/20 0.31
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SLC18A3 Q16572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869592 0.89 PRMT5 (0.31) MAPK1PRMT5WDR77
SCHEMBL30869423 0.82 PIM1 (0.40) KMT2AMEN1
SCHEMBL30869381 0.80 PIM1 (0.34)
SCHEMBL30869398 0.80 SMPD1 (0.35)
SCHEMBL30869489 0.80
SCHEMBL30869517 0.79 PIM1 (0.34)
SCHEMBL30869449 0.77 TSHR (0.35) TSHR
SCHEMBL30869731 0.77 MAPK1 (0.34) KMT2AMAPK1PRMT5WDR77MEN1
SCHEMBL30869825 0.77
SCHEMBL30869482 0.75 PIM1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed