SCHEMBL30869618

SCHEMBL30869618

c1cc(-c2ccc3c(c2)Oc2cc(-c4ccnc5[nH]ncc45)ccc2N3CCN2C[C@H]3C[C@@H]2CO3)c2cn[nH]c2n1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BRAF P15056 3/20 0.39
NUDT1 P36639 1/20 0.38
TNIK Q9UKE5 1/20 0.38
BRD4 O60885 1/20 0.37
PRKCQ Q04759 9/20 0.36
WNT1 P04628 2/20 0.35
GSK3B P49841 2/20 0.35
DYRK1A Q13627 2/20 0.35
TLR9 Q9NR96 1/20 0.35
TLR8 Q9NR97 1/20 0.35
TLR7 Q9NYK1 1/20 0.35
CSNK1D P48730 1/20 0.34
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
JAK2 O60674 1/20 0.34
ROCK2 O75116 1/20 0.34
PRKCD Q05655 1/20 0.34
ROCK1 Q13464 1/20 0.34
CHEK1 O14757 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869510 0.83 BRAF (0.41) BRAFWNT1GSK3BDYRK1A
SCHEMBL30869683 0.83 GSK3B (0.42) BRAFTNIKWNT1GSK3BDYRK1A
SCHEMBL30869562 0.81 CHRNA7 (0.43) BRAFPRKCQWNT1GSK3BDYRK1A
SCHEMBL30869532 0.79 ATR (0.38) BRAFWNT1GSK3BDYRK1A
SCHEMBL30869877 0.79 PIK3CD (0.48) NUDT1TNIKBRD4PRKCQTLR9
SCHEMBL30869723 0.76 PRKCQ (0.42) NUDT1TNIKBRD4PRKCQTLR9
SCHEMBL30869702 0.76 CHRNA7 (0.42) BRAFPRKCQWNT1GSK3BDYRK1A
SCHEMBL30869522 0.76 CHRNA7 (0.42) BRAFPRKCQWNT1GSK3BDYRK1A
SCHEMBL30869718 0.75 CHRNA7 (0.41) BRAFPRKCQWNT1GSK3BDYRK1A
SCHEMBL30869780 0.75 CHRNA7 (0.41) BRAFPRKCQWNT1GSK3BDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed