Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30869480 | 0.74 | PRKDC (0.37) | MAP3K11BRD4PIM1PIM3PIM2 | |
| SCHEMBL6221010 | 0.72 | ATM (0.57) | ATMICMTNR4A2PIM1PIM3 | |
| SCHEMBL16544662 | 0.70 | CYP11B1 (0.41) | NR1H2NR1H3BRD4 | |
| SCHEMBL19662767 | 0.70 | MET (0.55) | MAP3K11BRD4PIM1PIM3PIM2 | |
| SCHEMBL32683132 | 0.67 | KDM1A (0.48) | MAP3K11BRD4HTR1DHTR1BPIM1 | |
| SCHEMBL27328772 | 0.66 | MAP3K11 (0.39) | MAP3K11BRD4HTR1DHTR1B | |
| SCHEMBL31314342 | 0.66 | CA12 (0.43) | BACE1EGFR | |
| SCHEMBL16810784 | 0.66 | KDM4E (0.45) | NR1H2NR1H3 | |
| SCHEMBL1336445 | 0.66 | ATM (0.41) | ATMICMTAPPBACE1HTR1D | |
| SCHEMBL22631857 | 0.66 | ICMT (0.45) | ATMMAP3K11ICMTAPPBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583868-A2 | DYNAMIN ACTIVATORS | Walden Biosciences, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054661-A2 | DYNAMIN ACTIVATORS | WALDEN BIOSCIENCES (US) | 2024-03-14 | — | — | WO | disclosed |