SCHEMBL30869480

SCHEMBL30869480

Cc1c[nH]c2ccc(-c3ccc4c(c3)Oc3cc(-c5ccc6[nH]ccc6c5)ccc3N4CCN3CCOCC3)cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.37
MTOR P42345 2/20 0.37
CYP2C9 P11712 1/20 0.37
PIK3CA P42336 1/20 0.37
ATR Q13535 1/20 0.37
TDO2 P48775 2/20 0.36
MAP3K11 Q16584 3/20 0.35
SGK1 O00141 1/20 0.35
IKBKB O14920 1/20 0.35
AURKA O14965 1/20 0.35
CHUK O15111 1/20 0.35
PRKAB2 O43741 1/20 0.35
ROCK2 O75116 1/20 0.35
ABL1 P00519 1/20 0.35
NTRK1 P04629 1/20 0.35
INSR P06213 1/20 0.35
LCK P06239 1/20 0.35
CDK1 P06493 1/20 0.35
IGF1R P08069 1/20 0.35
MET P08581 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869770 0.93 PRKDC (0.37) PRKDCMTORCYP2C9PIK3CAATR
SCHEMBL30869719 0.84 KDM1A (0.42) PRKDCMTORCYP2C9PIK3CAATR
SCHEMBL30869715 0.84 PRKDC (0.40) PRKDCMTORCYP2C9PIK3CAATR
SCHEMBL32683132 0.79 KDM1A (0.48) TDO2MAP3K11PIM1PIM3PIM2
SCHEMBL30869710 0.78 WDR5 (0.38) PRKDCMTORCYP2C9PIK3CAATR
SCHEMBL32682881 0.76 WDR5 (0.43) PRKDCMTORCYP2C9PIK3CAATR
SCHEMBL30869459 0.76 PIM1 (0.45) PRKDCMTORCYP2C9PIK3CAATR
SCHEMBL30869516 0.76 CD274 (0.41) MTORPIK3CAMAP3K11FLT1KCNH2
SCHEMBL30869704 0.74 ATM (0.41) MAP3K11FLT1KCNH2PIM1PIM3
SCHEMBL30869456 0.73 EGFR (0.53) CYP2C9PIK3CAAURKAROCK2LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed