SCHEMBL30869836

SCHEMBL30869836

FC(F)(F)c1cc2cc(-c3ccc4c(c3)Sc3cc(-c5ccc6[nH]c(C(F)(F)F)cc6c5)ccc3N4CCN3CCOCC3)ccc2[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 13/20 0.46
CHRNA7 P36544 4/20 0.40
KCNH2 Q12809 4/20 0.40
MEN1 O00255 2/20 0.34
GMNN O75496 2/20 0.34
USP2 O75604 2/20 0.34
LMNA P02545 2/20 0.34
CYP3A4 P08684 2/20 0.34
MAPT P10636 2/20 0.34
MAPK1 P28482 2/20 0.34
PMP22 Q01453 2/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869782 0.80 CHRNA7 (0.38) CHRNA7KCNH2MAPTKDM4EALDH1A1
SCHEMBL30869561 0.79 CHRNA7 (0.47) CHRNA7KCNH2MEN1KMT2AKDM4E
SCHEMBL30869741 0.78 KDM1A (0.52) KDM1AMAPTALDH1A1
SCHEMBL32682887 0.78 EGFR (0.52) KDM1AMAPK1
SCHEMBL27324454 0.75 KDM1A (0.53) KDM1AALDH1A1
SCHEMBL32683132 0.73 KDM1A (0.48) KDM1A
SCHEMBL32682882 0.72 KDM1A (0.47) KDM1A
SCHEMBL30869758 0.72 KDM1A (0.47) KDM1A
SCHEMBL30869884 0.71 KDM1A (0.43) KDM1AUSP2CYP3A4ALDH1A1
SCHEMBL30869478 0.69 ROCK2 (0.51) KDM1ACHRNA7KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed