SCHEMBL30869741

SCHEMBL30869741

c1cc2ccc(-c3ccc4c(c3)Sc3cc(-c5ccc6cc[nH]c6c5)ccc3N4CCN3CCOCC3)cc2[nH]1

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 14/20 0.52
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PIK3CA P42336 3/20 0.41
MTOR P42345 2/20 0.41
PIK3CG P48736 1/20 0.40
ATR Q13535 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27324454 0.80 KDM1A (0.53) KDM1AALDH1A1
SCHEMBL32682887 0.79 EGFR (0.52) KDM1APIK3CA
SCHEMBL30869836 0.78 KDM1A (0.46) KDM1AALDH1A1MAPT
SCHEMBL32683132 0.78 KDM1A (0.48) KDM1A
SCHEMBL30869758 0.75 KDM1A (0.47) KDM1APIK3CA
SCHEMBL32682882 0.75 KDM1A (0.47) KDM1A
SCHEMBL30869827 0.73 KDM1A (0.64) KDM1AMAPT
SCHEMBL30869556 0.73 KDM1A (0.64) KDM1A
SCHEMBL32682893 0.73 KDM1A (0.50) KDM1A
SCHEMBL30869719 0.73 KDM1A (0.42) KDM1AALDH1A1MAPTHSD17B10PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 KDM1A 3264/4885ALDH1A1 4860/4885MAPT 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.