Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458995 | 1.00 | PRMT5 (0.46) | PRMT5WDR77GPR119BRD4KDM4E | |
| SCHEMBL30869882 | 1.00 | PRMT5 (0.46) | PRMT5WDR77GPR119BRD4KDM4E | |
| SCHEMBL30869808 | 0.94 | PRMT5 (0.48) | PRMT5WDR77GPR119BRD4KDM4E | |
| SCHEMBL25123922 | 0.94 | PRMT5 (0.48) | PRMT5WDR77GPR119BRD4KDM4E | |
| SCHEMBL30750569 | 0.93 | ALDH1A1 (0.44) | PRMT5WDR77GPR119BRD4KDM4E | |
| SCHEMBL30750580 | 0.88 | ALDH1A1 (0.46) | PRMT5WDR77GPR119BRD4KDM4E | |
| SCHEMBL23884184 | 0.87 | ACHE (0.51) | GPR119BRD4KDM4EPKML3MBTL1 | |
| SCHEMBL12805731 | 0.85 | ALDH1A1 (0.48) | KDM4E | |
| SCHEMBL15208916 | 0.84 | PRMT5 (0.48) | PRMT5WDR77GPR119KDM4EPKM | |
| SCHEMBL25123698 | 0.84 | GPR119 (0.47) | PRMT5WDR77GPR119BRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584275-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | Halda Therapeutics Opco, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054604-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |