Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11793572 | 0.78 | CES1 (0.50) | CES1IDO1MEN1ALDH1A1LMNA | |
| SCHEMBL30288157 | 0.78 | CES1 (0.50) | CES1IDO1MEN1ALDH1A1LMNA | |
| SCHEMBL30362942 | 0.72 | ALDH1A1 (0.46) | MEN1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL30843875 | 0.72 | CES1 (0.44) | CES1IDO1MEN1ALDH1A1LMNA | |
| SCHEMBL29250726 | 0.72 | CES1 (0.44) | CES1IDO1MEN1ALDH1A1LMNA | |
| SCHEMBL17699232 | 0.70 | CES1 (0.51) | CES1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL10941056 | 0.69 | CES1 (0.50) | CES1IDO1MEN1ALDH1A1LMNA | |
| SCHEMBL28356949 | 0.66 | CES1 (0.32) | CES1IDO1MEN1ALDH1A1LMNA | |
| SCHEMBL31506632 | 0.64 | CES1 (0.49) | CES1IDO1MEN1ALDH1A1LMNA | |
| SCHEMBL20669045 | 0.62 | S100A4 (0.48) | ALDH1A1LMNAHPGDKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583863-B2 | Synthetically modifiable ion channels | UNIVERSITY OF WYOMING (US) | 2026-03-24 | — | — | US | disclosed |
| US-20240300967-A1 | SYNTHETICALLY MODIFIABLE ION CHANNELS | UNIVERSITY OF WYOMING | 2024-09-12 | — | — | US | disclosed |
| US-11976078-B2 | Synthetically modifiable ion channels | UNIVERSITY OF WYOMING (US) | 2024-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300967-A1 | SYNTHETICALLY MODIFIABLE ION CHANNELS | KCNN2, KCNN1, HCN4 | CES1 4866/4885IDO1 2828/4885MEN1 543/4885 |
| US-12583863-B2 | Synthetically modifiable ion channels | HCN4, HCN3, HCN2 | CES1 4767/4885IDO1 3348/4885MEN1 1357/4885 |
| US-11976078-B2 | Synthetically modifiable ion channels | KCNN2, KCNN1, HCN4 | CES1 4866/4885IDO1 2828/4885MEN1 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.