Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | PLD1 | Q13393 | 5/20 | 0.49 |
| ▸ | PLD2 | O14939 | 4/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22869393 | 1.00 | DRD2 (0.63) | DRD2ALDH1A1CCR3PLD1PLD2 | |
| SCHEMBL30870247 | 0.89 | ALDH1A1 (0.53) | DRD2ALDH1A1CCR3CHRM1MAPK1 | |
| SCHEMBL22869530 | 0.89 | ALDH1A1 (0.53) | DRD2ALDH1A1CCR3CHRM1MAPK1 | |
| SCHEMBL22869384 | 0.88 | HSD11B1 (0.55) | DRD2ALDH1A1CHRM1MAPK1LMNA | |
| SCHEMBL30870340 | 0.88 | ALDH1A1 (0.52) | DRD2ALDH1A1CCR3CHRM1MAPK1 | |
| SCHEMBL22869836 | 0.88 | ALDH1A1 (0.52) | DRD2ALDH1A1CCR3CHRM1MAPK1 | |
| SCHEMBL30870175 | 0.88 | ALDH1A1 (0.52) | DRD2ALDH1A1CCR3CHRM1MAPK1 | |
| SCHEMBL22869678 | 0.88 | ALDH1A1 (0.52) | DRD2ALDH1A1CCR3CHRM1MAPK1 | |
| SCHEMBL30870196 | 0.88 | HSD11B1 (0.55) | DRD2ALDH1A1CHRM1MAPK1LMNA | |
| SCHEMBL22869548 | 0.87 | ALDH1A1 (0.52) | DRD2ALDH1A1CHRM1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | claimed |
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |