Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.60 |
| ▸ | PLD2 | O14939 | 5/20 | 0.54 |
| ▸ | PLD1 | Q13393 | 5/20 | 0.54 |
| ▸ | CCR5 | P51681 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047936 | 1.00 | HSD11B1 (0.60) | HSD11B1PLD2PLD1CCR5OPRM1 | |
| SCHEMBL8710318 | 0.92 | CHRM1 (0.51) | HSD11B1PLD2PLD1CCR5OPRM1 | |
| SCHEMBL31192530 | 0.92 | CHRM1 (0.51) | HSD11B1PLD2PLD1CCR5OPRM1 | |
| SCHEMBL16652901 | 0.89 | HSD11B1 (0.50) | HSD11B1PLD2PLD1CCR5OPRM1 | |
| SCHEMBL29198147 | 0.88 | CHRM1 (0.53) | HSD11B1CCR5OPRM1CHRM1CHRM2 | |
| SCHEMBL22587693 | 0.88 | HSD11B1 (0.56) | HSD11B1CCR5OPRM1CHRM1CHRM2 | |
| SCHEMBL318475 | 0.87 | HSD11B1 (0.60) | HSD11B1PLD2PLD1CCR5OPRM1 | |
| SCHEMBL28706708 | 0.87 | CCR5 (0.51) | HSD11B1PLD2PLD1CCR5OPRM1 | |
| SCHEMBL14146573 | 0.87 | CCR5 (0.51) | HSD11B1CCR5CHRM1DRD2CHRM2 | |
| SCHEMBL20599032 | 0.87 | CCR5 (0.49) | HSD11B1CCR5OPRM1CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924296-B | 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2024-09-17 | — | — | CN | disclosed |
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |