SCHEMBL398716

SCHEMBL398716

CCc1cccc(C(C)CC)c1N

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
GABRA1 P14867 5/20 0.39
GABRB2 P47870 5/20 0.39
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HTT P42858 1/20 0.33
ATP4A P20648 1/20 0.33
ATP4B P51164 1/20 0.33
ELANE P08246 3/20 0.33
RORC P51449 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683779 0.86 TSHR (0.56) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL22081599 0.85 TSHR (0.48) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL770339 0.84 GABRA1 (0.42) TSHRGABRA1GABRB2HPGDHTT
SCHEMBL29631719 0.84 GABRA1 (0.42) TSHRGABRA1GABRB2HPGDHTT
SCHEMBL6313117 0.82 GABRA1 (0.40) TSHRGABRA1GABRB2ALDH1A1HTT
SCHEMBL14647742 0.81 GABRA1 (0.43) TSHRGABRA1GABRB2ALDH1A1GAA
SCHEMBL300990 0.80 TSHR (0.50) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL3627333 0.79 TSHR (0.59) TSHRGABRA1GABRB2HTTRORC
SCHEMBL8838855 0.79 GABRA1 (0.42) TSHRGABRA1GABRB2ALDH1A1HTT
SCHEMBL10798080 0.78 TSHR (0.48) TSHRUSP2ALDH1A1GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115010606-B Synthesis method and application of 2-sec-butyl-6-ethylaniline 中国农业大学 2024-01-23 CN claimed
CN-115010606-A Synthesis method and application of 2-sec-butyl-6-ethylaniline 中国农业大学 2022-09-06 CN claimed
EP-0479943-A4 ADHESIVES AND METHOD FOR MAKING SAME 1992-09-16 EP claimed
EP-0479943-A1 ADHESIVES AND METHOD FOR MAKING SAME MARTIN MARIETTA ENERGY SYSTEMS, INC. (US) 1992-04-15 EP claimed
WO-1991000308-A1 ADHESIVES AND METHOD FOR MAKING SAME MARTIN MARIETTA ENERGY SYSTEMS, INC. (US) 1991-01-10 WO claimed
EP-0020138-B1 N-(2-AMINO-3-ETHYL-ALPHA-METHYLBENZYLIDENE)-2,6-DIETHYLANILINE AND ITS PREPARATION; ANTIOXIDANT ADDITIVE MIXTURES INCLUDING SAID COMPOUND; THE USE OF SAID COMPOUND, SAID ADDITIVE MIXTURES AND CERTAIN ALKYLATED ANILINES AS ANTIOXIDANTS FOR ORGANIC MATERIALS; AND ORGANIC MATERIALS AFFORDED ANTIOXIDANT PROTECTION AS AFORESAID ETHYL CORPORATION (US) 1983-06-22 EP claimed
US-4269720-A N-(2-AMINO-3-ETHYL-ALPHA-METHYLBENZYLIDENE)-2,6-DIETHYL ANILINE ETHYL CORPORATION (US) 1981-05-26 US claimed
EP-0020138-A2 N-(2-amino-3-ethyl-alpha-methylbenzylidene)-2,6-diethylaniline and its preparation; antioxidant additive mixtures including said compound; the use of said compound, said additive mixtures and certain alkylated anilines as antioxidants for organic materials; and organic materials afforded antioxidant protection as aforesaid ETHYL CORPORATION (US) 1980-12-10 EP claimed
CN-115010606-B Synthesis method and application of 2-sec-butyl-6-ethylaniline 中国农业大学 2024-01-23 CN disclosed
CN-115010606-B Synthesis method and application of 2-sec-butyl-6-ethylaniline 中国农业大学 2024-01-23 CN disclosed
CN-115010606-B Synthesis method and application of 2-sec-butyl-6-ethylaniline 中国农业大学 2024-01-23 CN disclosed
CN-115010606-A Synthesis method and application of 2-sec-butyl-6-ethylaniline 中国农业大学 2022-09-06 CN disclosed
CN-115010606-A Synthesis method and application of 2-sec-butyl-6-ethylaniline 中国农业大学 2022-09-06 CN disclosed
CN-115010606-A Synthesis method and application of 2-sec-butyl-6-ethylaniline 中国农业大学 2022-09-06 CN disclosed
EP-0055363-B1 PERYLENE TETRACARBOXYLIC-ACID DIIMIDES AND THEIR USE BASF Aktiengesellschaft (DE) 1983-12-14 EP disclosed
EP-0020138-B1 N-(2-AMINO-3-ETHYL-ALPHA-METHYLBENZYLIDENE)-2,6-DIETHYLANILINE AND ITS PREPARATION; ANTIOXIDANT ADDITIVE MIXTURES INCLUDING SAID COMPOUND; THE USE OF SAID COMPOUND, SAID ADDITIVE MIXTURES AND CERTAIN ALKYLATED ANILINES AS ANTIOXIDANTS FOR ORGANIC MATERIALS; AND ORGANIC MATERIALS AFFORDED ANTIOXIDANT PROTECTION AS AFORESAID ETHYL CORPORATION (US) 1983-06-22 EP disclosed
EP-0055363-A1 Perylene tetracarboxylic-acid diimides and their use BASF Aktiengesellschaft (DE) 1982-07-07 EP disclosed
US-4269720-A N-(2-AMINO-3-ETHYL-ALPHA-METHYLBENZYLIDENE)-2,6-DIETHYL ANILINE ETHYL CORPORATION (US) 1981-05-26 US disclosed
US-4269720-A N-(2-AMINO-3-ETHYL-ALPHA-METHYLBENZYLIDENE)-2,6-DIETHYL ANILINE ETHYL CORPORATION (US) 1981-05-26 US disclosed
EP-0020138-A2 N-(2-amino-3-ethyl-alpha-methylbenzylidene)-2,6-diethylaniline and its preparation; antioxidant additive mixtures including said compound; the use of said compound, said additive mixtures and certain alkylated anilines as antioxidants for organic materials; and organic materials afforded antioxidant protection as aforesaid ETHYL CORPORATION (US) 1980-12-10 EP disclosed