Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 4/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | CCR9 | P51686 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13331893 | 0.81 | AKR1C3 (0.44) | SMARCA2SMARCA4RECQLAKR1C3AKR1C2 | |
| SCHEMBL30184947 | 0.81 | SMARCA2 (0.37) | SMARCA2SMARCA4KDM4CAAK1RECQL | |
| SCHEMBL30872128 | 0.80 | ALDH1A1 (0.41) | SMARCA2SMARCA4AAK1CYP1A2 | |
| SCHEMBL30872131 | 0.80 | ALDH1A1 (0.41) | SMARCA2SMARCA4AAK1CYP1A2 | |
| SCHEMBL14903833 | 0.79 | CYP1A2 (0.45) | SMARCA2SMARCA4RECQLGRM5CCR9 | |
| SCHEMBL22548067 | 0.78 | RECQL (0.37) | SMARCA2SMARCA4AAK1RECQLAKR1C3 | |
| SCHEMBL15143115 | 0.77 | NAPRT (0.43) | CYP2D6CYP2C9HIF1A | |
| SCHEMBL27334496 | 0.75 | RECQL (0.35) | SMARCA2SMARCA4AAK1RECQLATR | |
| SCHEMBL28818554 | 0.74 | CYP2D6 (0.50) | CYP2D6CYP2C9HIF1ACYP1A2 | |
| SCHEMBL26639005 | 0.74 | SMARCA2 (0.44) | SMARCA2SMARCA4RECQLGRM5AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |