Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872131 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAAL3MBTL1GPR119ABCB11 | |
| SCHEMBL1979700 | 0.85 | CNR2 (0.50) | ALDH1A1GAAL3MBTL1GPR119ABCB11 | |
| SCHEMBL24355439 | 0.81 | GAA (0.49) | ALDH1A1GAAL3MBTL1ABCB11CYP1A2 | |
| SCHEMBL30872138 | 0.80 | SMARCA2 (0.38) | CYP1A2AAK1SMARCA2SMARCA4 | |
| SCHEMBL2183357 | 0.79 | GAA (0.40) | ALDH1A1GAAL3MBTL1GPR119ABCB11 | |
| SCHEMBL28008253 | 0.75 | PIN1 (0.49) | ALDH1A1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL30184947 | 0.74 | SMARCA2 (0.37) | ALDH1A1GAAL3MBTL1AAK1SMARCA2 | |
| SCHEMBL13332664 | 0.71 | GPR119 (0.44) | ALDH1A1GAAL3MBTL1GPR119CYP3A4 | |
| SCHEMBL1979197 | 0.71 | GPR119 (0.44) | ALDH1A1GAAL3MBTL1GPR119CYP3A4 | |
| SCHEMBL22548067 | 0.71 | RECQL (0.37) | AAK1SMARCA2SMARCA4NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |