Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 13/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872154 | 0.83 | HCRTR2 (0.37) | HCRTR2HCRTR1SLC6A7 | |
| SCHEMBL31351496 | 0.81 | HCRTR1 (0.60) | HCRTR2HCRTR1 | |
| SCHEMBL30872180 | 0.79 | HCRTR1 (0.43) | HCRTR2HCRTR1 | |
| SCHEMBL30872179 | 0.79 | PKM (0.38) | HCRTR2HCRTR1 | |
| SCHEMBL30872176 | 0.73 | KDM4E (0.47) | HCRTR2HCRTR1L3MBTL1MEN1KMT2A | |
| SCHEMBL30872161 | 0.70 | HCRTR1 (0.48) | HCRTR2HCRTR1 | |
| SCHEMBL30872171 | 0.70 | HCRTR1 (0.50) | HCRTR2HCRTR1 | |
| SCHEMBL15210509 | 0.69 | POLB (0.48) | PIK3CDPIK3CAPIK3CGPIK3CBL3MBTL1 | |
| SCHEMBL30872184 | 0.69 | HCRTR1 (0.43) | HCRTR2HCRTR1 | |
| SCHEMBL23013190 | 0.68 | EGFR (0.54) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024109672-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLE METHYL KETONE DERIVATIVE AND APPLICATION THEREOF | 江苏恩华药业股份有限公司 | 2024-05-30 | — | — | WO | disclosed |