Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 3/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924223 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GAAHPGDKDM4EKRAS | |
| SCHEMBL10216198 | 0.89 | CYP2A6 (0.44) | HPGDKDM4EDPP4NR1H2NR1H3 | |
| SCHEMBL8200797 | 0.87 | DPP4 (0.40) | ALDH1A1GAAHPGDKDM4EKRAS | |
| SCHEMBL27531475 | 0.85 | ALDH1A1 (0.38) | ALDH1A1GAAHPGDKDM4EKRAS | |
| SCHEMBL23809196 | 0.82 | ALDH1A1 (0.43) | ALDH1A1GAAHPGDKDM4EKRAS | |
| SCHEMBL25628271 | 0.81 | KRAS (0.43) | ALDH1A1GAAHPGDKDM4EKRAS | |
| SCHEMBL287031 | 0.81 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDKDM4EKRAS | |
| SCHEMBL27506477 | 0.77 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDKDM4EKRAS | |
| SCHEMBL12930760 | 0.77 | ALDH1A1 (0.45) | ALDH1A1GAAHPGDKDM4EKRAS | |
| SCHEMBL5541367 | 0.75 | ALDH1A1 (0.41) | ALDH1A1GAAHPGDKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300922-A1 | PROCESS FOR PREPARING EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2024-09-12 | — | — | US | disclosed |
| CN-117881670-A | Methods of making EGFR inhibitors | 缆图药品公司 | 2024-04-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300922-A1 | PROCESS FOR PREPARING EGFR INHIBITORS | EGFR, ERBB2, ERBB4 | ALDH1A1 2197/4885GAA 1002/4885HPGD 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.