Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924223 | 0.87 | ALDH1A1 (0.40) | DPP4NR1H2NR1H3CA1CA2 | |
| SCHEMBL30872206 | 0.87 | ALDH1A1 (0.40) | DPP4NR1H2NR1H3CA1CA2 | |
| SCHEMBL10216198 | 0.77 | CYP2A6 (0.44) | DPP4NR1H2NR1H3CA1CA2 | |
| SCHEMBL28393186 | 0.77 | TYMS (0.45) | ALDH1A1GAAHPGDKDM4EKMT2A | |
| SCHEMBL23809196 | 0.75 | ALDH1A1 (0.43) | ALDH1A1GAAHPGDKDM4EKMT2A | |
| SCHEMBL12306712 | 0.75 | MEN1 (0.43) | ALDH1A1GAAHPGDKDM4ELMNA | |
| SCHEMBL167078 | 0.74 | GABRA1 (0.55) | DPP4NR1H2NR1H3CA1CA2 | |
| SCHEMBL29414063 | 0.74 | GABRA1 (0.55) | DPP4NR1H2NR1H3CA1CA2 | |
| SCHEMBL28860690 | 0.73 | CLK4 (0.51) | CA12CA9 | |
| SCHEMBL287031 | 0.73 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121182-A | A METALLOCENE CATALYST FOR POLYMERIZATION OF ISOTACTIC POLYOLEFINS WITH HIGH RIGIDITY AND HIGH MELTING POINT, USEFUL AS INDUSTRIAL MATERIAL FOR AUTOMOBILES | JAPAN POLYOLAFINS CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |